# $Id: BUGS,v 1.4 2002-12-31 13:09:05 birney Exp $ Known Bugs Bioperl 1.2 =========== * The searchio.t test is failing on cygwin installations (and nowhere else). We need a developer who works with cygwin to help us out here. We suspect something to do with temporary file opening. Bioperl 0.9.0 ============= * Bio::Tools::Blast continues to cause problems for some people. As it is not actively maintained there are a slew of reported bugs for it that have not been fixed. * Bio::Tools::Run::Alignment::TCoffee - t_coffee binary does not get all parameters it needs when aligning (two) two DNA sequences (jitterbug #966). * Bio::Tools::Run::ClustalW and t/ClustalW will report errors for clustalw versions 1.8x due to a bug in clustalw. * Bio::DB::GenBank continues to have intermittent errors. Bio::DB::GDB is also unreliable at times and one can safely ignore errors from these during a make test. Bio::DB::GenBank is unable to download whole contig files as well as NCBI ref seqs like NT_* numbers unless the -format flag is passed in and specified as 'fasta' in the constructor. get_Stream_by_batch() also has intermittent errors which are being tracked down. Bioperl 0.7.2 ============= * NCBI has changed some of the cgi scripts for retrieving sequences online which as resulted in some of the DB methods from not working consistently. We are addressing these in the 0.9.x and 1.0 series of releases. We recommend using the Bio::DB::EMBL object that is part of the later releases. Additionally RefSeq Contigs are not properly downloaded, please see the bioperl list archives for information about potential workarounds and ongoing development effort to address these. Bioperl 0.7.1 ============= * Bio::Tools::BPlite does not parse and set frame properly for tblastx reports (Jitterbug bug # 978). * Bio::Tools::BPlite interface needs to be updated to fix parsing more than bl2seq report report (Jitterbug bug #940), this has been fixed on the main code trunk and will be part of the next major bioperl release. * If File::Temp is not installed, tempdirs are not cleaned up properly. This is fixed on main code trunk with the introduction of rmtree method in Bio::Root::IO, however, it is best to install File::Temp when running 0.7 branch code. * Bio::Tools::Blast does not allow users to run blast, instead use Bio::Tools::Run::StandAloneBlast to run local blasts. To submit jobs to a remote blast server like NCBI a module Bio::Tools::Run::RemoteBlast has been written but is part of the main trunk code and must be obtained through CVS until the next major bioperl release. Bioperl 0.7 =========== * Bio::Tools::BPlite doc error lists code synopsis code as my $parser = new BPlite(\*FH); should be my $parser = new Bio::Tools::BPlite(\*FH);